Xian-Guo Liu Selected Research

prolinedithiocarbamate (PDTC)

12/2010	Inhibition of NF-kappaB prevents mechanical allodynia induced by spinal ventral root transection and suppresses the re-expression of Nav1.3 in DRG neurons in vivo and in vitro.
6/2007	Peri-sciatic administration of recombinant rat TNF-alpha induces mechanical allodynia via upregulation of TNF-alpha in dorsal root ganglia and in spinal dorsal horn: the role of NF-kappa B pathway.

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Xian-Guo Liu Research Topics

Disease

35	Neuralgia (Stump Neuralgia) 03/2021 - 08/2006
33	Hyperalgesia 11/2021 - 05/2003
23	Pain (Aches) 01/2022 - 02/2006
8	Chronic Pain 01/2022 - 11/2015
8	Peripheral Nerve Injuries 01/2019 - 08/2010
6	Memory Disorders (Memory Loss) 11/2021 - 04/2011
6	Hypersensitivity (Allergy) 01/2019 - 08/2007
4	Neuroinflammatory Diseases 01/2022 - 01/2017
3	Neoplasms (Cancer) 07/2023 - 11/2010
3	Magnesium Deficiency (Deficiency, Magnesium) 11/2021 - 01/2017
3	Cystitis 11/2021 - 01/2019
3	Peripheral Nervous System Diseases (PNS Diseases) 01/2016 - 05/2014
2	Inflammation (Inflammations) 07/2023 - 03/2018
2	Acute Pain 01/2018 - 05/2016
2	Alzheimer Disease (Alzheimer's Disease) 09/2014 - 05/2013
2	Intervertebral Disc Displacement (Herniated Disc) 01/2012 - 05/2011
2	Sciatica (Sciatic Neuralgia) 01/2012 - 05/2011
1	Diarrhea 07/2023
1	Mucositis 07/2023
1	Colorectal Neoplasms (Colorectal Cancer) 07/2023
1	Pathologic Processes 01/2022
1	Musculoskeletal Pain 03/2021
1	Gliosis 01/2021
1	Cognitive Dysfunction 01/2019
1	Edema (Dropsy) 03/2018
1	Erythema 03/2018
1	Hyperplasia 03/2018
1	Nociceptive Pain 01/2018
1	Arthralgia (Joint Pain) 01/2018

Drug/Important Bio-Agent (IBA)

9	CytokinesIBA 01/2022 - 03/2013
9	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 10/2019 - 08/2006
7	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2019 - 08/2008
6	MagnesiumIBA 01/2021 - 05/2013
5	Proteins (Proteins, Gene)FDA Link 01/2022 - 05/2003
5	threonic acid (threonate)IBA 01/2021 - 09/2013
5	bulleyaconitine AIBA 01/2020 - 11/2015
4	Voltage-Gated Sodium ChannelsIBA 01/2018 - 11/2010
4	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 01/2017 - 11/2010
3	Cyclophosphamide (Cytoxan)FDA LinkGeneric 11/2021 - 01/2019
3	Interleukin-1beta (Interleukin 1 beta)IBA 01/2019 - 04/2012
3	Interleukin-6 (Interleukin 6)IBA 01/2018 - 03/2013
3	Neutralizing AntibodiesIBA 01/2018 - 03/2013
3	NeurosteroidsIBA 01/2017 - 01/2013
3	Thalidomide (Thalomid)FDA Link 05/2014 - 08/2006
2	Liver X ReceptorsIBA 01/2022 - 01/2017
2	Ion Channels (Ion Channel)IBA 01/2022 - 03/2021
2	salicylhydroxamic acid (SHAM)IBA 01/2019 - 01/2018
2	Interleukin-10 (Interleukin 10)IBA 01/2018 - 09/2013
2	CalpainIBA 01/2018 - 02/2015
2	Small Interfering RNA (siRNA)IBA 01/2018 - 11/2016
2	Therapeutic UsesIBA 01/2018 - 09/2013
2	AlkaloidsIBA 01/2018 - 01/2018
2	DiterpenesIBA 01/2018 - 01/2018
2	SodiumIBA 01/2018 - 02/2011
2	Antineoplastic Agents (Antineoplastics)IBA 01/2017 - 11/2010
2	Aminoglutethimide (Cytadren)FDA Link 01/2017 - 01/2016
2	Vincristine (Oncovin)FDA LinkGeneric 01/2017 - 01/2016
2	4'-chlorodiazepamIBA 01/2016 - 01/2013
2	Diazepam (Valium)FDA LinkGeneric 01/2016 - 02/2006
2	Paclitaxel (Taxol)FDA LinkGeneric 11/2015 - 11/2010
2	Type I Tumor Necrosis Factor ReceptorsIBA 05/2014 - 08/2006
2	src-Family KinasesIBA 04/2012 - 08/2010
2	Minocycline (Cyclops)FDA LinkGeneric 04/2012 - 11/2010
2	osthol (osthole)IBA 01/2012 - 05/2011
2	p38 Mitogen-Activated Protein KinasesIBA 08/2011 - 02/2011
2	prolinedithiocarbamate (PDTC)IBA 12/2010 - 06/2007
2	NF-kappa B (NF-kB)IBA 12/2010 - 06/2007
1	Fluorouracil (Carac)FDA LinkGeneric 07/2023
1	Sincalide FDA Link 07/2023
1	Non-Narcotic Analgesics (Analgesics, Non Narcotic)IBA 03/2021
1	Cytidine Monophosphate (CMP)IBA 03/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021
1	Liposomes (Liposome)IBA 01/2021
1	Clodronic Acid (Clodronate)IBA 01/2021
1	Estrogens (Estrogen)FDA Link 01/2021
1	Histamine (Histamine Dihydrochloride)FDA Link 01/2020
1	Chloroquine (Aralen)FDA LinkGeneric 01/2020
1	Glycogen Synthase (Synthase I)IBA 01/2019
1	Neuregulin-1 (Neuregulin 1)IBA 01/2019
1	CateninsIBA 01/2019
1	PD168393IBA 01/2019
1	N- (4- methoxybenzyl)- N'- (5- nitro- 1,3- thiazol- 2- yl)ureaIBA 01/2019
1	SB 216763IBA 01/2019
1	Calcitonin Gene-Related PeptideIBA 01/2019
1	theanineIBA 03/2018
1	Platelet Endothelial Cell Adhesion Molecule-1IBA 03/2018
1	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 03/2018
1	Conotoxins (Conotoxin)IBA 01/2018
1	N-Type Calcium Channels (N-Type Calcium Channel)IBA 01/2018
1	Tetrodotoxin (Tetradotoxin)IBA 01/2018
1	Carisoprodol (Soma)FDA LinkGeneric 01/2018

Therapy/Procedure

7	Spinal Injections 01/2018 - 03/2007
6	Ligation 11/2017 - 08/2007
4	Therapeutics 07/2023 - 03/2011
4	Intraperitoneal Injections 01/2016 - 08/2006
3	Oral Administration 01/2021 - 01/2018
2	Intravenous Injections 01/2021 - 01/2019
2	Drug Therapy (Chemotherapy) 01/2021 - 01/2017
2	Intradermal Injections 01/2020 - 08/2007
1	Pain Management 03/2021